Mouse Monoclonal [clone 056B-214.2.4.2] (IgG1) to Human Complement C6

• Gene Name:

  [C6]

• NCBI Gene ID:

  729

• Reactivity:

  Human

• Storage Conditions:

  4°C or -20°C.
  Store undiluted
  Avoid repeated freezing and thawing.
  Microcentrifugation recommended if solution contains precipitate.

• Specificity:

  Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.

• Other Gene Names:

  [C6; C6]

• Short Name:

  [Complement C6]

• Other Product Names:

  [complement component C6; Complement component C6; complement component C6; complement component 6]

• NCBI GI Number:

  169636415

• NCBI Accession Number:

  NP_000056.2

• NCBI GB Accession Number:

  NM_000065.3

• Uniprot Accession Number:

  P13671