Ceftizoxime

CAT: 0013-GTR19158622-01Size: 200 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19158622-01Size:200 mg

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Description

Ceftizoxime is a cephalosporin-based, potent antibacterial agent which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. (In Vitro) :Ceftizoxime is a new parenteral cephalosporin derivative which is more active against various gram-negative bacilli, including the opportunistic pathogens such as Enterobacter, Citrobacter species, and Serratia marcescens, than cephalosporins and cephamycins such as cefotiam, cefamandole, cefuroxime, cefotaxime, and cefmetazole. Ceftizoxime shows a broad spectrum of antibacterial activity against aerobic gram-positive and gram-negative bacteria. (In Vivo) :The therapeutic effect of Ceftizoxime in mice infected with a small inoculum size is almost the same as that of cefotaxime. Ceftizoxime is stable in biological fluids such as serum, urine, and tissue homogenates, but cefotaxime is unstable in rat tissue homogenates. Binding of ceftizoxime to serum protein in all species is the lowest of all the antibiotics: 31% for humans, 17% for dogs, and 32% for rats.

CAS Number

68401-81-0

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO : 25 mg/mL 65.21 mM

Smiles

CO\N=C (/C (=O) N[C@H]1[C@H]2SCC=C (N2C1=O) C (O) =O) c1csc (N) n1

Molecular Formula

C13H13N5O5S2

Molecular Weight

383.41

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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C39SD1054	Ceftizoxime
MBS5773041	Ceftizoxime sodium

Ceftizoxime

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