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Carbazochrome

CAT: 0013-GTR19158606-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19158606-01Size:1 g
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Description
Carbazochrome is an antihemorrhagic, or hemostatic, agent that will cease blood flow by causing the aggregation and adhesion of platelets in the blood to form a platelet plug, ceasing blood flow from an open wound. It is hoped that this drug can be used in the future for preventing excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on its effectiveness and the severity of possible side effects remains to be fairly inconclusive. Carbazochrome has been investigated for use in the treatment of hemorrhoids in a mixture with troxerutin. (In Vitro) :Carbazochrome (0.1-10 μM) inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3 in a concentration-dependent manner. Carbazochrome (0.1-1 μM), when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances. (In Vivo) :Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats.
CAS Number
69-81-8
Product Name Alternative
Carbazochrome | AC-17 | AC 17 | AC17 | Adona
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : 5 mg/mL (21.17 mM)
Smiles
OC1C2=C/C (=N/NC (=O) N) /C (=O) C=C2N (C1) C
Molecular Formula
C10H12N4O3
Molecular Weight
236.23
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(Z) -2- (3-hydroxy-1-methyl-6-oxo-1,2,3,6-tetrahydro-5H-indol-5-ylidene) hydrazine-1-carboxamide

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