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Kamebakaurine

CAT: 0013-GTR19158564-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158564-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kamebakaurin has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity.Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-κB) p50.Kamebakaurin has anti-neuroinflammatory activity via inhibition of c-Jun NH -terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells.
CAS Number
73981-34-7
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (297.25 mM)
Smiles
CC1 (CCC (C2 (C1CC (C34C2CCC (C3O) C (=C) C4=O) O) CO) O) C
Molecular Formula
C20H30O5
Molecular Weight
350.45
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Kaur-16-en-15-one, 1,7,14,20-tetrahydroxy-, (1alpha,7alpha,14R) -

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