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Fleroxacin

CAT: 0013-GTR19159179-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159179-01Size:500 mg
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Description
Fleroxacin, a quinolone, is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV. Like other quinolones and fluoroquinolones the compound eradicates bacteria by interfering with DNA replication (bacterial DNA replication, transcription, repair and recombination) . Fleroxacin is active against many Gram-positive and Gram-negative bacteria. (In Vivo) :Fleroxacin (Ro 23-6240) is a new trifluorinated quinolone exhibiting high activity against a broad spectrum of gram-negative and gram-positive bacteria. Fleroxacin is characterized pharmacokinetically by a long elimination half-life (9 to 10 h) and high concentrations in plasma (e.g., maximum concentration of 2.3 micrograms/ml after an oral dose of 200 mg) . Fleroxacin (Ro 23-6240) is effective against Haemophilus ducreyi in vitro. Fleroxacin (Ro 23-6240), 200 or 400 mg as a single oral dose, is efficacious therapy for microbiologically proven chancroid in patients who do not have concurrent HIV-1 infection. Among HIV-1-infected men, a single dose of 200 or 400 mg of fleroxacin is inadequate therapy for chancroid.
CAS Number
79660-72-3
Product Name Alternative
Fleroxacin, Quinodis, Megalocin, AM-833, Ro 236240
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : < 1 mg/mL
Smiles
CN1CCN (CC1) C2=C (C=C3C (=C2F) N (C=C (C3=O) C (=O) O) CCF) F
Molecular Formula
C17H18F3N3O3
Molecular Weight
369.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6,8-difluoro-1- (2-fluoroethyl) -7- (4-methylpiperazin-1-yl) -4-oxoquinoline-3-carboxylic acid

Alternative Products

CatalogName
M19364-01Fleroxacin
HY-B0414R-01Fleroxacin (Standard)
AR-F01530-01Fleroxacin Impurity A
HY-B0414AS-01Fleroxacin-d3 (hydrochloride)
AR-F01533-01Fleroxacin Impurity D
AR-F01532-01Fleroxacin Impurity C
AR-F01531-01Fleroxacin Impurity B

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