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β-Nicotinamide mononucleotide

CAT: 0013-GTR19158613-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158613-01Size:200 mg
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Description
Nicotinamide ribotide (NMN) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD biosynthesis. Instead of the deamidation to nicotinic acid nicotinamide is directly converted to NMN by nicotinamide phosphoribosyltransferase (NAMPT EC 2.4.2.12) . The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT EC 2.7.7.1) which is a member of the nucleotidyltransferase alpha/beta-phosphodiesterase superfamily catalyzes the reaction NMN + ATP Nicotinamide adenine dinucleotide (NAD) + PPi representing the final step in the biosynthesis of NAD. NAD is a molecule that plays a fundamental role as a cofactor in cellular redox reactions. Thus NMN is an important metabolite for the maintenance of normal NAD biosynthesis. Circulating NMN levels may play an important role in regulating cell function in physiological and pathophysiological conditions.
CAS Number
1094-61-7
Product Name Alternative
β-NM
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
H2O:83.33 mg/mL (249.33 mM; Need ultrasonic)
Smiles
NC (=O) c1ccc[n+] (c1) [C@@H]1O[C@H] (COP (O) ([O-]) =O) [C@@H] (O) [C@H]1O
Molecular Formula
C11H15N2O8P
Molecular Weight
334.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
((2R3S4R5R) -5- (3-carbamoylpyridin-1-ium-1-yl) -34-dihydroxytetrahydrofuran-2-yl) methyl hydrogen phosphate

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