Products for Research Use Only
RegisterLogin

C176

CAT: 0013-GTR19158400-01Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19158400-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
C-176 is a highly potent and covalent mouse STING inhibitor. (In Vitro) :C-176 strongly reduces STING-mediated, but not RIG-I- or TBK1-mediated, IFNβ reporter activity. Pretreatment with C-176 markedly reduce the CMA-mediated induction of serum levels of type I IFNs and IL-6. (In Vivo) :C-176 (750/375 nmol C-176 per mouse in 200 μL corn oil) significantly reduces the CMA-mediated induction of serum levels of type I IFNs and IL-6., without significant toxicity.C-176 results in a significant reduction in serum levels of type I IFNs and in a strong suppression of inflammatory parameters in the heart, with no evident signs of overt toxicity Trex1 / mice.C-176 demonstrates marked amelioration of various signs of systemic inflammation in Trex1 / mice.
CAS Number
314054-00-7
Product Name Alternative
C 176 | C-176 | STING inhibitor 1
Purity
>98% (HPLC)
Solubility
DMSO: 100 mg/mL
Smiles
[O-][N+] (=O) c1ccc (o1) C (=O) Nc1ccc (I) cc1
Molecular Formula
C11H7IN2O4
Molecular Weight
358.09
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (4-iodophenyl) -5-nitrofuran-2-carboxamide

Related Products

CatalogName
GTR19236201-01C175-0062
GTR18568930C17 Antibody
GTR19210824-01PRMT5-IN-C17
GTR18074281C17 Antibody
GTR18901908-01C17 peptide
GTR18042001-01CysLTR1 (C173) polyclonal antibody
GTR19275727-01Boc-C17-COOH
GTR18213132-01C17 polyclonal antibody
GTR19256461-01C17 Lyso PAF
GTR18273616C17 Conjugated Antibody

Alternative Products

CatalogName
M19948-01C176

Popular Products