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RGX-104 HCl

CAT: 0013-GTR19158207-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158207-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RGX-104 is a liver X receptor (LXR) agonist with potential immunomodulating and antineoplastic activities. It modulates innate immunity via transcriptional activation of the ApoE gene. (In Vivo) :Oral administration of GW3965 or RGX-104 hydrochloride to animals bearing palpable tumors significantly suppresses the growth of multiple cancer types. Strong tumor growth suppression is also observed in animals bearing large tumors. In some instances, the treatment causes partial or complete tumor regression. Responses are seen across a wide spectrum of malignancies, including lung cancer, melanoma, glioblastoma, and ovarian, renal cell, triple-negative breast, and colon cancer.
CAS Number
610318-03-1
Product Name Alternative
SB742881
Purity
>98% (HPLC)
Solubility
DMSO: 115 mg/mL (181.81 mM)
Smiles
Cl.C[C@H] (CCOc1cccc (CC (O) =O) c1) N (CC (c1ccccc1) c1ccccc1) Cc1cccc (c1Cl) C (F) (F) F
Molecular Formula
C34H34Cl2F3NO3
Molecular Weight
632.54
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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