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ECF506

CAT: 0013-GTR19157908-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157908-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ECF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM) eCF506, the first small molecule with subnanomolar IC50 for SRC that requires 3 orders of magnitude greater concentration to inhibit ABL. eCF506 exhibits excellent water solubility, an optimal DMPK profile and oral bioavailability, halts SRC-associated neuromast migration in zebrafish embryos without inducing life-threatening heart defects, and inhibits SRC phosphorylation in tumor xenografts in mice.
CAS Number
1914078-41-3
Purity
>98% (HPLC)
Solubility
DMSO:62.5 mg/mL (122.40 mM; Need ultrasonic)
Smiles
COc1cc (ccc1NC (=O) OC (C) (C) C) -c1nn (CCN2CCC (CC2) N (C) C) c2ncnc (N) c12
Molecular Formula
C26H38N8O3
Molecular Weight
510.63
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

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BA9011-5.1eCF506
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A13126-5ECF506 5mg
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A13126-100ECF506 100mg
HY-112096SECF506-d5
A13126-25ECF506 25mg
A13126-1ECF506 1mg

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