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8-Prenylnaringenin

CAT: 0013-GTR19157878-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157878-01Size:200 mg
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Description
8-Prenylnaringenin is a phytoestrogen with high estrogenic activity, In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days. 8-PN or TAM were investigated regarding their effect on cell shedding. In vivo, the lower tongue surface of mice was irradiated with graded single doses of 25 kV X-rays. The incidence, latency, and duration of the resulting mucosal ulcerations were analyzed after topical treatment with 8-PN, TAM or solvent. 8-PN or TAM prevented the volume reduction of the irradiated cell aggregates during the incubation period. This was the result of a higher residual cell number in the treated versus the untreated irradiated aggregates. In vivo, topical treatment with 8-PN or TAM significantly increased the latency of mucositis from 10.9 to 12.1 and 12.4 days respectively, while the ulcer incidence was unchanged.
CAS Number
53846-50-7
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (734.49 mM)
Smiles
CC (C) =CCC1=C2O[C@@H] (CC (=O) C2=C (O) C=C1O) C1=CC=C (O) C=C1
Molecular Formula
C20H20O5
Molecular Weight
340.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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