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RABBIT ANTI HUMAN PAI-1

CAT: 0544-MBS223369-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS223369-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
[PAI-1]
NCBI Gene ID
5054
Storage Conditions
Prior to reconstitution store at 4 °C. After reconstitution store at -20 °C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of reconstitution.
Specificity
This item specifically recognises human PAI-1 (plasminogen activator inhibitor-1), otherwise known as SERPINE1, a 45kDa serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis.

Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (very-low-density lipoprotein).
Other Gene Names
[SERPINE1; SERPINE1; PAI; PAI1; PAI-1; PLANH1; PAI1; PLANH1; PAI; PAI-1]
Short Name
[PAI-1]
Other Product Names
[plasminogen activator inhibitor 1; Plasminogen activator inhibitor 1; plasminogen activator inhibitor 1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serpin E1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Endothelial plasminogen activator inhibitor; Serpin E1]
NCBI GI Number
10835159
NCBI Accession Number
NP_000593.1
NCBI GB Accession Number
NM_000602.4
Uniprot Accession Number
P05121