RABBIT ANTI HUMAN INTERLEUKIN-17F

• NCBI Gene ID:

  112744

• Storage Conditions:

  Prior to reconstitution store at 4 °C. After reconstitution store at -20 °C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 12 months from date of reconstitution.

• Specificity:

  This item is specific for human IL-17F (interleukin-17F), a disulphide-linked homodimer consisting of two 133 amino acid chains, which belongs to the IL-17 gene family and shares the highest sequence homology with IL-17A.
  
  IL-17F is expressed by activated CD4+ T-cells and monocytes, and acts as a stimulator of cytokine production, including granulocyte colony-stimulating factor (GM-CSF), IL-6 and IL-8. IL-7F also stimulates the production of IL-2, MCP-1 (monocyte chemotactic protein-1) and TGFB (Transforming growth factor beta) by endothelial cells, and inhibits endothelial cell angiogenesis.This item has been used in neutralisation assays where 50% inhibition (ND50) of the biological activity of 50ng/ml of human IL-17F was achieved using 0.9-1.2ug/ml of antibody.

• Other Gene Names:

  [IL17F; IL17F; ML1; ML-1; CANDF6; IL-17F; IL-17F]

• Short Name:

  [IL-17F]

• Other Product Names:

  [interleukin-17F; Interleukin-17F; interleukin-17F; cytokine ML-1; interleukin 17F; Cytokine ML-1]

• NCBI GI Number:

  16418375

• NCBI Accession Number:

  NP_443104.1

• NCBI GB Accession Number:

  NM_052872.3

• Uniprot Accession Number:

  Q96PD4

• CAS Number:

  9007-83-4