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LTURM34

CAT: 0013-GTR19157781-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157781-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K .LTURM34 is more consistently active against the selected cell lines (11 of 16), but at best shows 54% inhibition against the HOP-92 non-small cell lung cancer line. LTURM34 displays effective inhibition of DNA-PK with excellent selectivity over the Class I PI3K isoforms (IC50s: 5.8 and 8.5 μM for PI3K β and δ, respectively) .
CAS Number
1879887-96-3
Purity
>98% (HPLC)
Solubility
DMSO:60 mg/mL (144.76 mM)
Smiles
O=c1nc (oc2c (cccc12) -c1cccc2c3ccccc3sc12) N1CCOCC1
Molecular Formula
C24H18N2O3S
Molecular Weight
414.48
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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BA3949-10LTURM34
A19994-100LTURM34 100mg
A19994-200LTURM34 200mg
A19994-10LTURM34 10mg
A19994-5LTURM34 5mg
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A19994-50LTURM34 50mg
A19994-25LTURM34 25mg
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