RABBIT ANTI APAF1 (aa12-28)

• Gene Name:

  [APAF1]

• NCBI Gene ID:

  317

• Reactivity:

  Mouse

• Storage Conditions:

  Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.

• Specificity:

  Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. This item recognises a 130kD band in Western blots.

• Other Gene Names:

  [APAF1; APAF1; CED4; APAF-1; KIAA0413; APAF-1]

• Short Name:

  [APAF1]

• Other Product Names:

  [apoptotic protease-activating factor 1 isoform b; Apoptotic protease-activating factor 1; apoptotic protease-activating factor 1; apoptotic peptidase activating factor 1]

• NCBI GI Number:

  4502123

• NCBI Accession Number:

  NP_001151.1

• NCBI GB Accession Number:

  NM_001160.2

• Uniprot Accession Number:

  O14727

• CAS Number:

  9007-83-4