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RABBIT ANTI PPAR GAMMA

CAT: 0544-MBS221541-01Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS221541-01Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
[PPAR GAMMA]
NCBI Gene ID
5468
Reactivity
Dog (Expected from Sequence), Duck (Expected from Sequence), Guinea Pig (Expected from Sequence), Hamster (Expected from Sequence), Macaque (Expected from Sequence), Mink (Expected from Sequence), Mouse (Expected from Sequence), Rabbit (Expected from Sequ
Storage Conditions
Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Specificity
This item detects human peroxisome proliferator-activated receptor ? (PPARG), a member of the nuclear hormone receptor subfamily of transcription factors. Upon activation, PPARG forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARG is principally involved in the cellular assimilation of lipids, with key roles in adipocyte differentiation and adipogenesis.

Two alternatively spliced isoforms of PPARG exist, termed PPARG1 and PPARG2, which are identical except for an additional 30 amino acids at the N-terminus of PPARG2. This results in a predominant adipocyte localisation for PPARG2, whilst PPARG1 is ubiquitously expressed.

PPARG has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.
Other Gene Names
[PPARG; PPARG; GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; NR1C3; PPAR-gamma]
Short Name
[PPAR GAMMA]
Other Product Names
[peroxisome proliferator-activated receptor gamma isoform 1; Peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma; PPAR-gamma; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; Nuclear receptor subfamily 1 group C member 3]
NCBI GI Number
116284368
NCBI Accession Number
NP_005028.4
NCBI GB Accession Number
NM_005037.5
Uniprot Accession Number
P37231

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