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Camalexin

CAT: 0013-GTR19157749-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157749-01Size:100 mg
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Description
Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.Camalexin shows antiproliferative activity against a human breast cancer cell line. For the oomycetes, Phytophthora and Pythium Nep1-like proteins are the initial triggers of Camalexin synthesis and formation of ROS. ROS appear to be of general relevance for Camalexin formation. In a screen for enhanced susceptibility to Alternaria brassicicola the esa1 mutant is identified, which shows delayed Camalexin induction. Particularly in response to ROS inducing agents reduced Camalexin levels are synthesized. This crucial role for ESA1 is confirmed by the inability of esa1 mutants to synthesize Camalexin in response to Leptosphaeria maculans.
CAS Number
135531-86-1
Purity
>98% (HPLC)
Solubility
DMSO : 120 mg/mL (599.22 mM; Need ultrasonic)
Smiles
C12=C (C=CC=C2) NC=C1C3=NC=CS3
Molecular Formula
C11H8N2S
Molecular Weight
200.26
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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