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Tenilsetam

CAT: 0013-GTR19157698-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157698-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tenilsetam is an endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer's disease (AD) treatment.In vitro, tenilsetam inhibited endothelial proliferation at lower doses, while inducing apoptosis at high doses. Leucocyte adhesion was only inhibited at high doses. Sprouting angiogenesis of bovine retinal endothelial cells was promoted at lower doses (< or = 10 mM) . At micromolar concentrations, endothelial VEGF expression was upregulated by 100%. Long-term treatment with the AGE-inhibitor and iron-chelating compound tenilsetam inhibits the formation of acellular capillaries without correcting pericyte loss. The compound has dose-dependent effects on endothelial cell function.
CAS Number
86696-86-8
Product Name Alternative
Piperazinone,3- (2-thienyl) - (9CI)
Purity
>98% (HPLC)
Smiles
O=C1NCCN[C@]1 ([H]) c2ccc[s]2
Molecular Formula
C8H10N2OS
Molecular Weight
182.24
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
MBS3612141-01Tenilsetam

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