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Gluten Exorphin C

CAT: 0013-GTR19157597-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157597-01Size:200 mg
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Description
Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.Gluten Exorphin C, isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten, was considered as a δ-opioid receptor-selective ligand.Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC50s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity.
CAS Number
142479-62-7
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : 100 mg/mL (169.00 mM)
Smiles
CC[C@H] (C) [C@H] (NC (=O) [C@@H]1CCCN1C (=O) [C@@H] (N) Cc1ccc (O) cc1) C (=O) N[C@@H] (CO) C (=O) N[C@@H] (CC (C) C) C (O) =O
Molecular Formula
C29H45N5O8
Molecular Weight
591.7
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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