MOUSE ANTI HUMAN CD55

• Gene Name:

  [CD55]

• NCBI Gene ID:

  1604

• Storage Conditions:

  Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.

• Specificity:

  This item recognises the CD55 antigen, a 70kD glycoprotein also known as Decay Accelerating Factor (DAF). Distributed on erythrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. Found specifically at the foetal-maternal interfaces in placenta.CD55 has reduced expression on individuals with paroxysmal nocturnal haemoglobinuria. This antibody has a functional binding affinity to erythrocytes of 8.7 x 107 M-1. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. BRIC 216 recognises the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF.

• Other Gene Names:

  [CD55; CD55; CR; TC; DAF; CROM; CR; DAF]

• Short Name:

  [CD55]

• Other Product Names:

  [complement decay-accelerating factor isoform 1 preproprotein; Complement decay-accelerating factor; complement decay-accelerating factor; CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CD_antigen: CD55]

• NCBI GI Number:

  10835143

• NCBI Accession Number:

  NP_000565.1

• NCBI GB Accession Number:

  NM_000574.4

• Uniprot Accession Number:

  P08174

• CAS Number:

  9007-83-4