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Sulbutiamine

CAT: 0013-GTR19157443-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157443-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sulbutiamine is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death. (In Vitro) :Sulbutiamine shows neuroprotective effects on hippocampal CA1 pyramidal neurons subjected to oxygen-glucose deprivation. Sulbutiamine enhances electrophysiological properties such as excitatory synaptic transmissions and intrinsic neuronal membrane input resistance in a concentration-dependent manner. Sulbutiamine attenuates apoptotic cell death induced by serum deprivation and stimulates GSH and GST activity in a dose dependent manner. Furthermore, sulbutiamine decreases the expression of cleaved caspase-3 and AIF.
CAS Number
3286-46-2
Product Name Alternative
Bisibuthiamine
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:75 mg/mL (106.70 mM)
Smiles
CC (C) C (=O) OCC\C (SS\C (CCOC (=O) C (C) C) =C (\C) N (Cc1cnc (C) nc1N) C=O) =C (/C) N (Cc1cnc (C) nc1N) C=O
Molecular Formula
C32H46N8O6S2
Molecular Weight
702.89
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
[ (Z) -4-[ (4-Amino-2-methylpyrimidin-5-yl) methyl-formylamino]-3-[[ (Z) -2-[ (4-amino-2-methylpyrimidin-5-yl) methyl-formylamino]-5- (2-methylpropanoyloxy) pent-2-en-3-yl]disulfanyl]pent-3-enyl] 2-methylpropanoate

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