MOUSE ANTI HUMAN CD55

CAT: 0544-MBS213200-01Size: 0.2 mgDry Ice: NoHazardous: No
CAT#:0544-MBS213200-01Size:0.2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
[CD55]
NCBI Gene ID
1604
Storage Conditions
Store at 4 °C or at -20 °C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Specificity
This item recognises the CD55 antigen, a 70kD glycoprotein also known as Decay Accelerating Factor (DAF). Distributed on erythrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. Found specifically at the foetal-maternal interfaces in placenta. CD55 has reduced expression on individuals with paroxysmal nocturnal haemoglobinuria. This antibody has a functional binding affinity to erythrocytes of 8.7 x 107 M-1. The antigen is pronase and trypsin resistant and chymotrypsin sensitive. BRIC 216 recognises the consensus region 3 of the DAF molecule, which contains the functional site, and the antibody blocks the function of DAF.
Other Gene Names
[CD55; CD55; CR; TC; DAF; CROM; CR; DAF]
Short Name
[CD55]
Other Product Names
[complement decay-accelerating factor isoform 1 preproprotein; Complement decay-accelerating factor; complement decay-accelerating factor; CD55 antigen; CD55 molecule, decay accelerating factor for complement (Cromer blood group); CD_antigen: CD55]
NCBI GI Number
10835143
NCBI Accession Number
NP_000565.1
NCBI GB Accession Number
NM_000574.4
Uniprot Accession Number
P08174

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