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Proxyphylline

CAT: 0013-GTR19157422-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19157422-01Size:1 g
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Description
Proxyphylline is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant vasodilator and bronchodilator. (In Vitro) :Proxyphylline has shown vasodilatory and cardiac stimulatory effects. Proxyphylline produces an increase in the coronary flow associated with a definite positive inotropic effect. Proxyphylline inhibits tracheal PDE-activity and half-maximum relaxation of tracheal smooth muscle is obtained with 100 μg/mL proxyphylline (In Vivo) :Proxyphylline exhibits bronchodilatory effect. Proxyphylline inhibits cAMP and cGMP hydrolysis in human lung tissue. The apparent inhibition constant of proxyphylline is 0.06-0.7 mM at low cAMP concentrations and it is 1.0 mM at high cAMP concentrations.
CAS Number
603-00-9
Product Name Alternative
7- (2-Hydroxypropyl) theophylline
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:47 mg/mL (197.28 mM)
Smiles
CC (O) Cn1cnc2n (C) c (=O) n (C) c (=O) c12
Molecular Formula
C10H14N4O3
Molecular Weight
238.24
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
7- (2-hydroxypropyl) -13-dimethyl-37-dihydro-1H-purine-26-dione

Alternative Products

CatalogName
C3278-5000Proxyphylline
HY-B1742R-01Proxyphylline (Standard)
A16821-200Proxyphylline 200mg
RM-P183301-01(R) -Proxyphylline
RM-P183302-01(S) -Proxyphylline
A16821-500Proxyphylline 500mg
A16821-10mM-DProxyphylline 10mM * 1mL in DMSO
RM-D091804-01Diprophylline EP Impurity D; Proxyphylline

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