Products for Research Use Only
RegisterLogin

MOUSE ANTI HUMAN C8

CAT: 0544-MBS212936-01Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0544-MBS212936-01Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
[C8]
NCBI Gene ID
732
Storage Conditions
Store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Specificity
This item recognises complement component 8 (C8), a 151 kDa member of the complement C6/C7/C8/C9 family, present in blood serum. C8 is a terminal component of the complement system, part of both the complement membrane attack complex (MAC), and important to MAC assembly. C8 binds to the C5b-7 complex, anchored to the membrane, creating C5b-8. C5b-8 binds C9 and catalyses the polymerization of C9 molecules to form C5-b9 (MAC). C8 is thought to contain lipid binding sites, facilitating the insertion of MAC into the membrane.

Defects in the alpha chain of C8 can result in complement C8 deficiency type I. Furthermore, C8 deficiencies can cause recurring bacterial infections, in particular from Neisseria meningitides.
Other Gene Names
[C8B; C8B; C82]
Short Name
[C8]
Other Product Names
[complement component C8 beta chain preproprotein; Complement component C8 beta chain; complement component C8 beta chain; complement component 8 subunit beta; complement component 8, beta polypeptide; Complement component 8 subunit beta]
NCBI GI Number
4557391
NCBI Accession Number
NP_000057.1
NCBI GB Accession Number
NM_000066.2

Related Products

CatalogName
MBS147391-01Human Complement C8
MBS8247280-01Anti-Complement C8 beta Antibody
MBS8248278-01Anti-Complement C8 beta Antibody
MBS7620918-01Recombinant Human C8 gamma
MBS5756561C8 Ceramide
MBS3600530J8-C8
MBS565700-01C8-Dihydroceramide
MBS5799512C8 Dihydroceramide
MBS5816324PP-C8
MBS808198-01C8 Ceramide

Alternative Products

CatalogName
GTR19306744Mouse Anti-human IgA
40R-1015Mouse anti Human IgG3
10R-I129AMouse anti Human IgG4
10R-I128AMouse anti Human IgG2
10R-I127AMouse anti Human IgG1
10-I20AMouse anti Human IgM
10C-CR6046M4Mouse anti Human IgE
31-3400-0.1Mouse Anti-Human CD11b
31-3326-0.1Mouse Anti-Human CD61
31-3314-0.1Mouse Anti-Human CD49d

Popular Products