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MOUSE ANTI HUMAN COMPLEMENT FACTOR B (Bb FRAGMENT)

CAT: 0544-MBS212918-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS212918-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
NCBI Gene ID
629
Storage Conditions
Prior to reconstitution store at 4 °C. After reconstitution store at 4 °C or at -20 °C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Specificity
This item recognises the Bb fragment of 90 kDa human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.
Other Gene Names
[CFB; CFB; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; BF; BFD; GBG]
Short Name
[COMPLEMENT FACTOR B]
Other Product Names
[complement factor B preproprotein; Complement factor B; complement factor B; B-factor, properdin; C3 proaccelerator; C3 proactivator; C3/C5 convertase; glycine-rich beta glycoprotein; glycine-rich beta-glycoprotein; properdin factor B; complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; GBG; PBF2; Properdin factor BCleaved into the following 2 chains:Complement factor B Ba fragment; Complement factor B Bb fragment]
NCBI GI Number
67782358
NCBI Accession Number
NP_001701.2
NCBI GB Accession Number
NM_001710.5
Uniprot Accession Number
P00751

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PE71156Human Complement Factor Ba (fragment of factor B)
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