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DOPEXAMINE

CAT: 0013-GTR19157032-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157032-01Size:200 mg
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Description
Dopexamine is a dopaminergic agonistDopexamine hydrochloride has interesting vasodilator properties, with marked intrinsic agonist activity at beta-2 adrenoreceptors and a lesser agonist activity at dopaminergic receptors (DA1 and DA2) . Dopexamine hydrochloride is responsible for an inhibition of neuronal re-uptake of catecholamines (uptake-1), producing an indirect stimulation of cardiac beta 1-receptors. Dopexamine hydrochloride improves cardiac performance by a marked vasodilation and a mild inotropic activity. The specific activity at dopaminergic receptors increases cerebral, myocardial, splanchnic and renal blood flows. These haemodynamic effects are associated with an increase in diuresis and natriuresis. These benefits are achieved without side effects such as an increased myocardial oxygen consumption, although induced tachycardia may be responsible for chest pain/anginae pain in patients with ischaemic heart disease.
CAS Number
86197-47-9
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Smiles
Oc1ccc (CCNCCCCCCNCCc2ccccc2) cc1O
Molecular Formula
C22H32N2O2
Molecular Weight
356.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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HY-106562Dopexamine
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