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TRIM

CAT: 0013-GTR19157021-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19157021-01Size:1 g
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Description
TRIM is an inhibitor of nNOS.TRIM is a poor inhibitor of bovine aortic endothelial NOS with an IC50 of 1057.5 microM. TRIM (10-50 mg kg-1) administered i.p. exhibits dose-related antinociceptive activity in the mouse (assessed as inhibition of late phase formalin-induced hindpaw licking behaviour) with an ED50 of 85.8 mumol kg-1. In contrast, TRIM (50 mg kg-1, i.p.) failed to influence mean arterial blood pressure in the urethane-anaesthetized mouse.
CAS Number
25371-96-4
Product Name Alternative
1- (2-Trifluoromethylphenyl) imidazole
Field of Research
Immunology & Inflammation
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (1178.30 mM)
Smiles
FC (F) (F) c1ccccc1-n1ccnc1
Molecular Formula
C10H7F3N2
Molecular Weight
212.17
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

Trim

1-[2-(trifluoromethyl)phenyl]imidazole is a member of imidazoles.

CAS Number25371-96-4
PubChem CID1359
IUPAC Name1-[2-(trifluoromethyl)phenyl]imidazole
Molecular FormulaC10H7F3N2
Molecular Weight212.17
XLogP2.6
Topological Polar Surface Area17.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count15
Formal Charge0
Complexity217
SMILES
C1=CC=C(C(=C1)C(F)(F)F)N2C=CN=C2
InChI
InChI=1S/C10H7F3N2/c11-10(12,13)8-3-1-2-4-9(8)15-6-5-14-7-15/h1-7H
InChIKey
WZBWBNCQUTXYEL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Trim
CAS: 25371-96-4
CID: 1359
Formula: C10H7F3N2
MW: 212.17
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight212.17
XLogP32.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass212.05613272
Monoisotopic Mass212.05613272
Topological Polar Surface Area17.8 Ų
Heavy Atom Count15
Formal Charge0
Complexity217
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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sc-51711TRIM (TRIM-04)
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NB500-485PCPMouse Monoclonal TRIM Antibody (TRIM-04) [PerCP]
NB500-485PEMouse Monoclonal TRIM Antibody (TRIM-04) [PE]
NB500-485FMouse Monoclonal TRIM Antibody (TRIM-04) [FITC]
NB500-485HMouse Monoclonal TRIM Antibody (TRIM-04) [HRP]
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