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TY-52156

CAT: 0013-GTR19156952-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156952-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM) . TY-52156 displays submicromolar potency and a high degree of selectivity for the S1P3 receptor. TY-52156 inhibits the S1P3 receptor-dependent increase in [Ca2+]i. TY-52156 (10 μM; 10 min) inhibits S1P-induced p44/p42 MAPK phosphorylation.After oral administration in vivo, TY-52156 (10 mg/kg, 30 mg/kg; p.o.) inhibits S1P3 receptor-induced bradycardia.
CAS Number
934369-14-9
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (274.52 mM)
Smiles
CC (C) (C) C (=O) C (\NNc1ccc (Cl) cc1) =N\c1ccc (Cl) cc1
Molecular Formula
C18H19Cl2N3O
Molecular Weight
364.27
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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Alternative Products

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C4797-100TY 52156
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A12265-2TY-52156 2mg
A12265-5TY-52156 5mg
A12265-100TY-52156 100mg
A12265-50TY-52156 50mg
A12265-200TY-52156 200mg
A12265-25TY-52156 25mg
A12265-10TY-52156 10mg

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