Products for Research Use Only

Acetamiprid

CAT: 0013-GTR19156864-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19156864-01Size:1 g
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Description
Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. Acetamiprid decreases in body weight and mildly affected spermatogenesis. Acetamiprid disrupts subsequent testosterone biosynthesis by decreasing the rate of conversion of cholesterol to testosterone and by preventing cholesterol from entering the mitochondria within the Leydig cells. These effects caused reproductive damage to the rats. Acetamiprid decreases the expression of testosterone-metabolism genes, nAChR subunit genes, and proliferation-associated genes in mice.
CAS Number
135410-20-7
Purity
>98% (HPLC)
Solubility
DMSO:97 mg/mL (435.62mM)
Smiles
CN (Cc1ccc (Cl) nc1) C (C) =NC#N
Molecular Formula
C10H11ClN4
Molecular Weight
222.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.