Products for Research Use Only
RegisterLogin

ML-180

CAT: 0013-GTR19156823-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19156823-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ML-180 is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .ML-180 (0.5-5 μM; 24 hours) shows a significant inhibition of cyclin-D1 and cyclin-E1 expression in hepatic cells, but has little effect on repression in SK-OV-3 cells. ML-180 (5 μM; 24 hours) leads to a rapid decrease of LRH-1 expression and efficiently represses endogenous LRH-1 signaling. ML-180 has a statistically significant decrease of both LRH-1 and SHP mRNA in adrenal glands and pancreatic tissue.
CAS Number
863588-32-3
Product Name Alternative
SR1848
Purity
>98% (HPLC)
Solubility
DMSO:11 mg/mL (28.28 mM; Need ultrasonic)
Smiles
Clc1cccc (c1) N1CCN (CC1) c1cc (=O) n (C2CCCCC2) c (=O) [nH]1
Molecular Formula
C20H25ClN4O2
Molecular Weight
388.89
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Related Products

CatalogName
GTR19240457-01XH161-180
GTR19194196Jmv 180
GTR19229856-01SSR 180
GTR19263911-01RS130-180
GTR19297924-01Reactive red 180
GTR19035078-01PLP (180-199)
GTR17963034Clec-180 Antibody
GTR18077460DOCK 180 antibody
GTR19265925-01Anticancer agent 180
GTR19262798-01Antitumor agent-180

Alternative Products

CatalogName
T12075-01ML-180
A22701-50ML-180 50mg
A22701-5ML-180 5mg
A22701-10ML-180 10mg
A22701-100ML-180 100mg
A22701-25ML-180 25mg
A22701-2ML-180 2mg
A22701-1ML-180 1mg
A22701-10mM-DML-180 10mM * 1mL in DMSO
D2004-3-180Solution 3 Neutralizing Buffer (180 mL)

Popular Products