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Alpha-Terpineol

CAT: 0013-GTR19156776-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156776-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor. The antifungal effects of citral, eugenol, nerolidol and alpha-Terpineol on Trichophyton mentagrophytes were investigated. METHODS AND RESULTS:Citral over 0.1 mg/ml strongly inhibited the hyphal growth of T. mentagrophytes, and the antifungal activity of alpha-Terpineol was less effective. The morphological changes of the fungus exposed to the terpenes were observed by electron microscopy. The hyphae were distorted and collapsed at 0.2, 0.4 and 1 mg/ml of eugenol, nerolidol and alpha-Terpineol respectively, and cell membrane and organelles were irreversibly damaged at 0.2 mg/ml citral. CONCLUSIONS:These suggested that four terpenes possess antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption.
CAS Number
98-55-5
Purity
>98% (HPLC)
Solubility
DMSO:247 mg/mL (1600.78 mM)
Smiles
CC1=CCC (CC1) C (C) (C) O
Molecular Formula
C10H18O
Molecular Weight
154.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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