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GSK2795039

CAT: 0013-GTR19156742-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156742-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays) . GSK2795039 (25 μM; 24 hours) decreases the combinatory effect of FeSO4 and LPS-increased levels of apoptosis. It also reduced the presence of caspase-3-positive PC12 cells.GSK2795039 (i.p.; 100 mg/kg; 1 hour before) reduces activity in a murine model of acute pancreatitis. It also decreases the levels of serum amylase triggered by systemic injection of cerulein.
CAS Number
1415925-18-6
Purity
>98% (HPLC)
Solubility
DMSO:31 mg/mL (68.8 mM)
Smiles
CC (C) n1cc (-c2ccc3CCN (C) c3c2) c2c (NS (=O) (=O) c3ccn (C) n3) ccnc12
Molecular Formula
C23H26N6O2S
Molecular Weight
450.56
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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BA2730-25GSK2795039
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A20998-25GSK2795039 25mg

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