Products for Research Use Only
RegisterLogin

Isobavachromene

CAT: 0013-GTR19156639-02Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19156639-02Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Isobavachromene is an inhibitor of NADH-Ubiquinone oxidoreductase and ornithine decarboxylase. Isobavachromene has antifungal activity.Estrogenic activities of ethanol extract and its active components from Psoralea corylifolia L. were studied using various in vitro assays. The main components from ethanol extract were analyzed to be bakuchiol, psoralen, isobavachalcone, Isobavachromene, and bavachinin. In a fractionation procedure, hexane and chloroform fractions showed estrogenic activity in yeast transactivation assay and E-screen assay. In yeast transactivation assay, ethanol extract, hexane, and chloroform fractions showed significantly higher activities at a concentration of 1.0 ng/ml, and bakuchiol at the concentration of 10 (-6) M was showed the highest activity, especially, which was higher than genistein at the same concentration.
CAS Number
52801-22-6
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 66.67 mg/mL (206.82 mM)
Smiles
O=C (C1=CC=C2C (C=CC (C) (C) O2) =C1O) /C=C/C3=CC=C (O) C=C3
Molecular Formula
C20H18O4
Molecular Weight
322.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

4-Hydroxylonchocarpin

Isobavachromene has been reported in Mundulea sericea, Dorstenia dinklagei, and other organisms with data available.

CAS Number52801-22-6
PubChem CID5889042
IUPAC Name(E)-1-(5-hydroxy-2,2-dimethylchromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one
Molecular FormulaC20H18O4
Molecular Weight322.4
XLogP4.5
Topological Polar Surface Area66.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count24
Formal Charge0
Complexity514
SMILES
CC1(C=CC2=C(O1)C=CC(=C2O)C(=O)/C=C/C3=CC=C(C=C3)O)C
InChI
InChI=1S/C20H18O4/c1-20(2)12-11-16-18(24-20)10-8-15(19(16)23)17(22)9-5-13-3-6-14(21)7-4-13/h3-12,21,23H,1-2H3/b9-5+
InChIKey
IQHPDUUSMBMDGN-WEVVVXLNSA-N
Chemical Structure
2D Structure
2D structure of 4-Hydroxylonchocarpin
CAS: 52801-22-6
CID: 5889042
Formula: C20H18O4
MW: 322.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight322.4
XLogP34.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass322.12050905
Monoisotopic Mass322.12050905
Topological Polar Surface Area66.8 Ų
Heavy Atom Count24
Formal Charge0
Complexity514
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
TN1774-01Isobavachromene
300473Isobavachromene discontinued

Popular Products