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NS13001

CAT: 0013-GTR19156487-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19156487-01Size:200 mg
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Description
NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance calcium-activated potassium channels) . The EC50s are 1.8 and 0.14 μM for SK2 and SK3, respectively. NS13001 holds promise as a potential therapeutic agent for treatment of spinocerebellar ataxia type 2 (SCA2) and possibly other cerebellar ataxias.
CAS Number
1063331-94-1
Product Name Alternative
N- (4-chlorophenyl) -2- (3,5-dimethylpyrazol-1-yl) -9-methylpurin-6-amine | N- (4-Chlorophenyl) -2- (3,5-dimethyl-1H-pyrazol-1-yl) -9-methyl-9H-purin-6-amine
Purity
>98% (HPLC)
Solubility
DMSO: 90 mg/mL (254.37 mM; Need ultrasonic)
Smiles
Cc1cc (C) nn1-c (nc1Nc (cc2) ccc2Cl) nc2c1ncn2C
Molecular Formula
C17H16ClN7
Molecular Weight
353.81
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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CatalogName
BA6902-25NS13001
A15833-100NS13001 100mg
A15833-10NS13001 10mg
A15833-50NS13001 50mg
A15833-25NS13001 25mg
A15833-5NS13001 5mg
A15833-2NS13001 2mg
A15833-10mM-DNS13001 10mM * 1mL in DMSO

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