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JHU 37152

CAT: 0013-GTR19155825-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155825-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JHU 37152 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 5 nM and 0.5 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.
CAS Number
2369979-67-7
Purity
>98% (HPLC)
Solubility
DMSO:72 mg/mL (200.65 mM) ; Ethanol:24 mg/mL (66.88 mM)
Smiles
FC1=C2C (NC3=CC=C (Cl) C=C3N=C2N4CCN (CC) CC4) =CC=C1
Molecular Formula
C19H20ClFN4
Molecular Weight
358.85
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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