Products for Research Use Only

Tolebrutinib

CAT: 0013-GTR19155592-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155592-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tolebrutinib is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor (IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively) . It exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS) .
CAS Number
1971920-73-6
Product Name Alternative
SAR442168 | PRN2246
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (219.53 mM; Need ultrasonic)
Smiles
C=CC (N (CCC1) C[C@@H]1N (c (ccnc1N) c1N1c (cc2) ccc2Oc2ccccc2) C1=O) =O
Molecular Formula
C26H25N5O3
Molecular Weight
455.51
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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