PID/MTA2 Polyclonal Antibody

• Storage Conditions:

  This antibody is stable for at least one (1) year at -20 °C. Avoid multiple freeze-thaw cycles.

• Specificity:

  PID/MTA2 [This rabbit antibody recognizes aa 652-668 of human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. This antibody does not cross-react with MTA1.]
  This antibody recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. This antibody does not cross-react with MTA1.

• Short Name:

  [PID/MTA2]

• CAS Number:

  9007-83-4