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Bmf (NT) Polyclonal Antibody

CAT: 0544-MBS194181-01Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0544-MBS194181-01Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Storage Conditions
This antibody is stable for at least one (1) year at -20 °C. Avoid multiple freeze-thaw cycles.
Specificity
Bmf (NT) [This rabbit antibody recognizes an epitope of aa 2-14 at the N-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein.]
This antibody recognizes an epitope at the N-terminus of human Bmf (Bcl-2- Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiaing the downstream apoptotic program. Bmf is constitutively expressed in many tissues.
Short Name
[Bmf (NT)]

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