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Prunasin

CAT: 0804-HY-N1548-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1548-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prunasin is an orally active cyanogenic glucoside and the main metabolite of Amygdalin. Prunasin can specifically inhibit rat DNA polymerase β (IC50: 98 μM). Prunasin has anti-inflammatory and anti-fibrotic activities. Prunasin can be used in the research of diseases such as liver fibrosis[1][2].
CAS Number
99-18-3
UNSPSC
12352005
Hazard Statement
H301, H360
Target
DNA/RNA Synthesis
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/prunasin.html
Purity
99.56
Solubility
H2O : ≥ 50 mg/mL
Smiles
N#C[C@@H](C1=CC=CC=C1)O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
Molecular Formula
C14H17NO6
Molecular Weight
295.29
Precautions
H301, H360
References & Citations
[1]Mizushina Y, et al. The cyanogenic glucoside, prunasin (D-mandelonitrile-beta-D-glucoside), is a novel inhibitor of DNA polymerase beta. J Biochem. 1999;126 (2) :430-436.|[2]Zhang C, et al. Pharmacokinetics and anti-liver fibrosis characteristics of amygdalin: Key role of the deglycosylated metabolite prunasin. Phytomedicine. 2022 May;99:154018.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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