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Avoralstat

CAT: 0013-GTR19154763-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154763-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Avoralstat is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. (In Vitro) :C1 inhibitor (C1INH) is the primary regulator of contact activation, both by inhibiting the conversion of prekallikrein to plasma kallikrein (PKK) by FXIIa, and by directly inhibiting PKK. PKK cleaves high molecular weight kininogen, releasing bradykinin, whose actions are responsible for the signs and symptoms of hereditary angioedema (HAE) .
CAS Number
918407-35-9
Product Name Alternative
BCX4161
Purity
>98% (HPLC)
Solubility
DMSO:50 mg/mL (97.36 mM; Need ultrasonic)
Smiles
COc (c (C=C) c1) cc (-c2ccc (C (NCC3CC3) =O) nc2C (O) =O) c1C (Nc (cc1) ccc1C (N) =N) =O
Molecular Formula
C28H27N5O5
Molecular Weight
513.54
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

CatalogName
BA6068-10Avoralstat
A21102-5Avoralstat 5mg
A21102-50Avoralstat 50mg
A21102-10Avoralstat 10mg
A21102-2Avoralstat 2mg
A21102-100Avoralstat (BCX4161) 100mg
RM-A254001-01Avoralstat Impurity 1
A21102-25Avoralstat (BCX4161) 25mg
A21102-1Avoralstat (BCX4161) 1mg
A21102-10mM-DAvoralstat (BCX4161) 10mM * 1mL in DMSO

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