Replication Factor C p37 Monoclonal Antibody

This antibody recognizes the p37 subunit of human and yeast (S.cerevisiae) Replication Factor C (RFC).RFC is a heteropentameric protein consisting of p140, p40, p38, p37, and p36 subunits, RFC participates in targeting DNA polymerase ä processivity factor (PCNA) on to a primed DNA template during DNA synthesis and repair. RFC has also been associated with DNA repair in conjunction with a PCNA-like heterotrimer of Hus1, Rad1, and Rad9.
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