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IGP-1

CAT: 0013-GTR19154392-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154392-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IGP-1
CAS Number
27031-00-1
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Mitochondrial glyceraldehyde-3-phosphate dehydrogenase inhibitor
Form
Powder
Solubility
Soluble in DMSO up to 50 mg/ml
Molecular Formula
C17H415N3O3
Molecular Weight
309.3
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
A potent and cell permeable inhibitor of the mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH), IC50=6.3 M, which is selective over the cytosolic enzyme1. It does not block pyruvate uptake into cells or mitochondria and has no direct effect on glycolysis in synaptosomes. This novel inhibitor is a unique tool which may be used to investigate the role of glycerol-3-phosphate metabolism in isolated and intact systems.
Other Product Names
N-[4- (1H-Benzoimidazol-2-yl) -phenyl]-succinamic acid

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