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Sugammadex

CAT: 0013-GTR19154254-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154254-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sugammadex is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia. It is the first selective relaxant binding agent (SRBA) . Sugammadex is a modified γ-cyclodextrin, with a lipophilic core and a hydrophilic periphery. This gamma cyclodextrin has been modified from its natural state by placing eight carboxyl thio ether groups at the sixth carbon positions. These extensions extend the cavity size allowing greater encapsulation of the rocuronium molecule. These negatively charged extensions electrostatically bind to the quaternary nitrogen of the target as well as contribute to the aqueous nature of the cyclodextrin.
CAS Number
343306-71-8
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Smiles
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].O=C (CCSC[C@H]1O[C@H]2O[C@@H]3[C@@H] (CSCCC ([O-]) =O) O[C@@H] (O[C@@H]4[C@@H] (CSCCC ([O-]) =O) O[C@H] (O[C@@H]5[C@@H] (CSCCC ([O-]) =O) O[C@H] (O[C@@H]6[C@@H] (CSCCC ([O-]) =O) O[C@H] (O[C@@H]7[C@@H] (CSCCC ([O-]) =O) O[C@@H] (O[C@@H]8[C@@H] (CSCCC ([O-]) =O) O[C@H] (O[C@@H]9[C@@H] (CSCCC ([O-]) =O) O[C@@H] (O[C@H]1[C@@H] ([C@H]2O) O) [C@H] (O) [C@H]9O) [C@H] (O) [C@H]8O) [C@H] (O) [C@H]7O) [C@H] (O) [C@H]6O) [C@H] (O) [C@H]5O) [C@H] (O) [C@H]4O) [C@H] (O) [C@H]3O) [O-]
Molecular Formula
C72H104NA8O48S8
Molecular Weight
2178.00554466248
Notes
For research use only.

Alternative Products

CatalogName
RM-S075426-01Sugammadex-Ss- Sugammadex (Dimer)
RM-S075436-01Sugammadex-S-Sugammadex Dimer
MBS5785951Sugammadex
RM-S075465-01Mono Hydroxy Of Sugammadex; Monohydroxy Sugammadex
FS157329-01Sugammadex sodium
HY-B0079-01Sugammadex (sodium)
AR-S02202-01Monohydroxy Sugammadex
CS-O-49187Sugammadex octasulfoxide

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