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Micafungin

CAT: 0013-GTR19154240-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19154240-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. It inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. It received final approval from the U.S. Food and Drug Administration (FDA) on March 16, 2005. Micafungin works by way of concentration-dependent inhibition of 1,3-beta-D-glucan synthase resulting in reduced formation of 1,3-beta-D-glucan, which is an essential polysaccharide comprising one-third of the majority of Candida spp. cell walls. This decreased glucan production leads to osmotic instability and thus cellular lysis.
CAS Number
235114-32-6
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Smiles
CCCCCOC1=CC=C (C2=CC (C3=CC=C (C (N[C@H]4C[C@H] ([C@H] (NC ([C@@H]5[C@H] ([C@H] (CN5C ([C@H] ([C@@H] (CC (N) =O) O) NC ([C@H] ([C@@H] ([C@H] (C6=CC (OS (=O) (O) =O) =C (O) C=C6) O) O) NC ([C@@H]7C[C@H] (CN7C ([C@H] ([C@H] (O) C) NC4=O) =O) O) =O) =O) =O) C) O) =O) O) O) =O) C=C3) =NO2) C=C1
Molecular Formula
C56H71N9O23S
Molecular Weight
1270.27
Notes
For research use only.

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