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Osilodrostat (LCI699) phosphate

CAT: 0013-GTR19153855-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19153855-01Size:100 mg
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Description
Osilodrostat (LCI699) phosphate is a potent, orally active11β-hydroxylase (CYP11B1) inhibitor with an IC50 value of 35 nM. Osilodrostat phosphate is a potent, orally aldosterone synthase (CYP11B2) inhibitor with IC50 values of 0.7 nM and 160 nM for human aldosterone synthase and rat aldosterone synthase, respectively. Osilodrostat phosphate inhibits aldosterone and corticosterone synthesis. Osilodrostat phosphate has blood pressure lowering ability. Osilodrostat phosphate can be used for research of Cushing syndrome (CS) .
CAS Number
1315449-72-9
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Smiles
P (=O) (O) (O) O.FC1C=C (C#N) C=CC=1[C@H]1CCC2=CN=CN12
Molecular Formula
C13H13FN3O4P
Molecular Weight
325.2321870327
Notes
For research use only.

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