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CPI-455

CAT: 0013-GTR19153822-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19153822-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.
CAS Number
1628208-23-0
Purity
>98%
Smiles
Cl[H].O=C1C (=C (C2C ([H]) =C ([H]) C ([H]) =C ([H]) C=2[H]) N=C2C (C#N) =C ([H]) N ([H]) N12) C ([H]) (C ([H]) ([H]) [H]) C ([H]) ([H]) [H]
Molecular Formula
C16H15CLN4O
Molecular Weight
314.7695
Notes
For research use only.

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DQC20823-01CPI-455
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