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Ztz240

CAT: 0804-HY-115823-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-115823-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ztz240 is a chemical modulator of voltage-gated potassium channel Kv7 (KCNQ) (KCNQ2 and 3: EC50=6.1 μM; KCNQ4: EC50=12.2 μM) . ztz240 can be used in analgesia and anti-epileptic research[1].
CAS Number
325457-98-5
UNSPSC
12352005
Hazard Statement
H301-H311-H331
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ztz240.html
Smiles
O=C(C1=CC=C(C=C1)F)NC2=CN=C(C=C2)Cl
Molecular Formula
C12H8ClFN2O
Molecular Weight
250.66
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P403+P233-P405-P501
References & Citations
[1]Gao Z, et al. Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactions[J]. Journal of Biological Chemistry, 2010, 285 (36) : 28322-28332.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Voltage-gated potassium channel

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