NBD-GPP

CAT: 0013-GTR19152119Size: 20 ulDry Ice: NoHazardous: No

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CAT#:0013-GTR19152119Size:20 ul

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

NBD-GPP is a fluorescent analog of geranyl pyrophosphate (GPP) . It serves as lipid donor for farnesyltransferase (FTase) -one of the three mammalian protein prenyltransferases. The attachment of the NBD-geranyl group to protein substrates allows for efficient fluorescence based FTase activity assays and inhibitor screening.

Product Name Alternative

3,7-dimethyl-8- (7-nitro-benzo[1,2,5]oxadiazol-4-ylamino), -octa-2,6-diene-1-pyrophosphate, Fluorescent lipid donor for protein farnesyltransferase (FTase)

Concentration

1 mM

Purity

≥ 95% (HPLC)

Form

Liquid (Supplied as 1 mM solution in 25 mM (NH 4) 2CO3)

Smiles

C1 (ccc (c2c1non2) [N+] (=O) [O-]) NC/C (=C/CC/C (=C/COP (=O) (O) OP (=O) (O) O) /C) /C

Molecular Formula

C16H22N4O10P2

Molecular Weight

Theoretical MW: 492.31 g/mol

Storage Conditions

Store at -20 °C

Notes

For research use only.

Applications Notes

Spectroscopic Propertie: λexc 480 nm, λem 530 nm, ε 11.0 L mmol-1 cm-1 (pH 7.5) .

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NBD-GPP

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