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Bestatin

CAT: 0804-HY-B0134-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0134-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N) /APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects[1][2].
CAS Number
58970-76-6
Product Name Alternative
Ubenimex
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Aminopeptidase; Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Bestatin.html
Purity
99.98
Solubility
DMSO : 8.33 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O
Molecular Formula
C16H24N2O4
Molecular Weight
308.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Hossain A, et al. Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice. Exp Eye Res. 2016 Aug;149:100-6|[2]Qian X, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2016 May-Jun;23 (3) :e680-9.|[3]Lis M, et al. The effects of bestatin on humoral response to sheep erythrocytes in non-treated and cyclophosphamide-immunocompromised mice. Immunopharmacol Immunotoxicol. 2013 Feb;35 (1) :133-8|[4]Poloz Y, et al. Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum. Eukaryot Cell. 2012 Apr;11 (4) :545-57
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
CD13

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CatalogName
B040-5MGBestatin

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