Products for Research Use Only
RegisterLogin

Palovarotene

CAT: 0013-GTR19160332-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19160332-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Palovarotene, also known as RO-3300074 and R-667, is a highly selective retinoic acid receptor gamma (RAR-γ) agonist that is under investigation as a potential treatment for emphysema. Phase I clinical trials of palovarotene in patients with emphysema demonstrated that the drug is well tolerated, with improvements observed in markers of emphysema progression. Emphysema is characterized by the destruction of alveoli and alveolar ducts within the lungs. Retinoid signaling is believed to play a role in alveologenesis, with the retinoic acid receptor gamma thought to be required for alveolar formation.
CAS Number
410528-02-8
Product Name Alternative
RO-3300074 | RO 3300074 | RO3300074 | R-667
Purity
>98% (HPLC)
Solubility
DMSO : 19.5 mg/mL. 47.04 mM
Smiles
O=C (O) c1ccc (cc1) /C=C/c3cc4c (cc3Cn2cccn2) C (C) (C) CCC4 (C) C
Molecular Formula
C27H30N2O2
Molecular Weight
414.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- ((1E) -2- (5,5,8,8-Tetramethyl-3- (1H-pyrazol-1-ylmethyl) -5,6,7,8-tetrahydronaphthalen-2-yl) ethenyl) benzoic acid

Alternative Products

CatalogName
MBS3607498-01palovarotene
A12430-100Palovarotene 100mg
A12430-50Palovarotene 50mg
sc-478071Palovarotene-13C4
A12430-5Palovarotene 5mg
sc-478074Palovarotene Deuterated
A12430-25Palovarotene 25mg

Popular Products