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Bilastine

CAT: 0013-GTR19159901-02Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159901-02Size:25 mg
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Description
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives) . It exerts its effect as a selective histamine H1 receptor antagonist, and has a potency similar to cetirizine and is superior to fexofenadine. It was developed in Spain by FAES Farma. Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
CAS Number
202189-78-4
Product Name Alternative
Bilastine trade name Bilaxten
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 49.3 mg/mL; 106.34 mM
Smiles
CCOCCn1c (nc2ccccc12) C1CCN (CCc2ccc (cc2) C (C) (C) C (O) =O) CC1
Molecular Formula
C28H37N3O3
Molecular Weight
463.62
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (4- (2- (4- (1- (2-ethoxyethyl) -1H-benzo[d]imidazol-2-yl) piperidin-1-yl) ethyl) phenyl) -2-methylpropanoic acid

Chemical Information

Bilastine

Bilastine is a member of benzimidazoles.

CAS Number202189-78-4
PubChem CID185460
IUPAC Name2-[4-[2-[4-[1-(2-ethoxyethyl)benzimidazol-2-yl]piperidin-1-yl]ethyl]phenyl]-2-methylpropanoic acid
Molecular FormulaC28H37N3O3
Molecular Weight463.6
XLogP2.3
Topological Polar Surface Area67.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count10
Heavy Atom Count34
Formal Charge0
Complexity641
SMILES
CCOCCN1C2=CC=CC=C2N=C1C3CCN(CC3)CCC4=CC=C(C=C4)C(C)(C)C(=O)O
InChI
InChI=1S/C28H37N3O3/c1-4-34-20-19-31-25-8-6-5-7-24(25)29-26(31)22-14-17-30(18-15-22)16-13-21-9-11-23(12-10-21)28(2,3)27(32)33/h5-12,22H,4,13-20H2,1-3H3,(H,32,33)
InChIKey
ACCMWZWAEFYUGZ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Bilastine
CAS: 202189-78-4
CID: 185460
Formula: C28H37N3O3
MW: 463.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight463.6
XLogP32.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count10
Exact Mass463.28349205
Monoisotopic Mass463.28349205
Topological Polar Surface Area67.6 Ų
Heavy Atom Count34
Formal Charge0
Complexity641
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B082-10MGBilastine
AR-B05570-01Desethoxyethane Bilastine (Bilastine Impurity 14)
CS-O-15080Bilastine-d6

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